
Pomalidomide-amino-PEG3-NH2 hydrochloride
CAS No. 2380273-75-4
Pomalidomide-amino-PEG3-NH2 hydrochloride( —— )
Catalog No. M35170 CAS No. 2380273-75-4
Pomalidomide-amino-PEG3-NH2 hydrochloride is an E3 ligase ligand-linker conjugate containing a pomalidomide-based cereblon ligand and a linker, which can be used to synthesize PROTACs.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 61 | Get Quote |
![]() ![]() |
5MG | 86 | Get Quote |
![]() ![]() |
10MG | 125 | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NamePomalidomide-amino-PEG3-NH2 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionPomalidomide-amino-PEG3-NH2 hydrochloride is an E3 ligase ligand-linker conjugate containing a pomalidomide-based cereblon ligand and a linker, which can be used to synthesize PROTACs.
-
DescriptionPomalidomide-amino-PEG3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
-
In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In Vivo——
-
Synonyms——
-
PathwayPROTACs
-
TargetE3 Ligase Ligand
-
RecptorLigand for E3 Ligase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2380273-75-4
-
Formula Weight498.91
-
Molecular FormulaC21H27ClN4O8
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (200.44 mM; Ultrasonic )
-
SMILESCl.O=C(NC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3)COCCOCCOCCN
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.?
molnova catalog



related products
-
VH 298
A potent, specific cell-active VHL E3 ubiquitin ligase inhibitor that inhibits VHL/HIF-α interaction with Kd of 90 nM in ITC assays.
-
PROTAC-VHL-ligand
PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.
-
VL285
VL285 is a potent VHL ligand degrading HaloTag7 fusion proteins.